中国真菌学杂志

参考文献

[1] BONGOMIN F,GAGO S,OLADELE R O,et al.Global and multi-national prevalence of fungal diseases-estimate precision[J].J Fungi,2017,3(4):57-85.

[2] ROBBINS N,CAPLAN T,COWEN L E.Molecular evolution of antifungal drug resistance[J].Annu Rev Microbiol,2017,71(1):753-775.

[3] ROMáN E,PRIETO D,ALONSO-MONGE R,et al.New insights of CRISPR technology in human pathogenic fungi[J].Future Microbiol,2019,14(14):1243-1255.

[4] UTHAYAKUMAR D,SHARMA J,WENSING L,et al.CRISPR-based genetic manipulation of Candida species:Historical perspectives and current approaches[J].Front Genome Ed,2021,2:606281-606303.DOI:10.3389/fgeed.2020.606281.

[5] JIANG F,DOUDNA J A.CRISPR-Cas9 structures and mechanisms[J].Annu Rev Biophys,2017,46(1):505-529.

[6] BRANDSMA I,VAN GENT D C.Pathway choice in DNA double strand break repair:observations of a balancing act[J].Genome Integr,2012,3(1):9-18.

[7] FULLER K K,CHEN S,LOROS J J,et al.Development of the CRISPR/Cas9 System for targeted gene disruption in Aspergillus fumigatus[J].Eukaryotic cell,2015,14(11):1073-1080.

[8] UMEYAMA T,HAYASHI Y,SHIMOSAKA H,et al.CRISPR/Cas9 genome editing to demonstrate the contribution of Cyp51A Gly138Ser to azole resistance in Aspergillus fumigatus[J].Antimicrob Agents Chemother,2018,62(9):e00894-00818.

[9] HUANG L G,DONG H Z,ZHENG J W,et al.Highly efficient single base editing in Aspergillus niger with CRISPR/Cas9 cytidine deaminase fusion[J].Microbiol Res,2019,223-225:44-50.DOI:10.1016/j.micres.2019.03.007.

[10] WANG P,MITCHELL A P,BAHN Y-S,et al.Two distinct approaches for CRISPR-Cas9-mediated gene editing in Cryptococcus neoformans and related species[J].mSphere,2018,3(3):e00208-00218.

[11] LIN J,FAN Y,LIN X.Transformation of Cryptococcus neoformans by electroporation using a transient CRISPR-Cas9 expression (TRACE) system[J].Fungal Genet Biol,2020,138:103364-103371.DOI:10.1016/j.fgb.2020.103364.

[12] VYAS V K,BARRASA M I,FINK G R.A Candida albicans CRISPR system permits genetic engineering of essential genes and gene families[J].Science Advances,2015,1(3):e1500248-e1500248.

[13] LOMBARDI L,OLIVEIRA-PACHECO J,BUTLER G,et al.Plasmid-based CRISPR-Cas9 gene editing in multiple Candida species[J].mSphere,2019,4(2):e00125-00119.

[14] RAINHA J,RODRIGUES J L,RODRIGUES L R.CRISPR-Cas9:A powerful tool to efficiently engineer Saccharomyces cerevisiae[J].Life,2021,11(1):13-28.

[15] NORTON E L,SHERWOOD R K,BENNETT R J.Development of a CRISPR-Cas9 system for efficient genome editing of Candida lusitaniae[J].mSphere,2017,2(3):e00217-00217.

[16] ZHANG C,MENG X,WEI X,et al.Highly efficient CRISPR mutagenesis by microhomology-mediated end joining in Aspergillus fumigatus[J].Fungal Genet Biol,2016,86:47-57.DOI:10.1016/j.fgb.2015.12.007.

[17] 贺小圆，赵明峰.念珠菌耐药机制的研究进展[J].中国真菌学杂志，2015,10(1):49-53.

[18] MORIO F,LOMBARDI L,BINDER U,et al.Precise genome editing using a CRISPR-Cas9 method highlights the role of CoERG11 amino acid substitutions in azole resistance in Candida orthopsilosis[J].J Antimicrob Chemother,2019,74(8):2230-2238.

[19] BALLARD E,WEBER J,MELCHERS W J G,et al.Recreation of in-host acquired single nucleotide polymorphisms by CRISPR-Cas9 reveals an uncharacterised gene playing a role in Aspergillus fumigatus azole resistance via a non-cyp51A mediated resistance mechanism[J].Fungal Genet Biol,2019,130:98-106.DOI:10.1016/j.fgb.2019.05.005.

[20] MARTEL C M,PARKER J E,WARRILOW A G S,et al.Complementation of a Saccharomyces cerevisiae ERG11/CYP51 doxycycline-regulated mutant and screening of the azole sensitivity of Aspergillus fumigatus isoenzymes CYP51A and CYP51B[J].Antimicrob Agents Chemother,2010,54(11):4920-4923.

[21] PéREZ-CANTERO A,MARTIN-VICENTE A,GUARRO J,et al.Analysis of the contribution of cyp51 genes to azole resistance in Aspergillus section nigri with the CRISPR-Cas9 technique[J].Antimicrob Agents Chemother,2021,65(5):e01996-01920.

[22] RYBAK J M,DOORLEY L A,NISHIMOTO A T,et al.Abrogation of triazole resistance upon deletion of CDR1 in a clinical isolate of Candida auris[J].Antimicrob Agents Chemother,2019,63(4):e00057-00019.

[23] RYBAK J M,MU?OZ J F,BARKER K S,et al.Mutations in TAC1B:a novel genetic determinant of clinical fluconazole resistance in Candida auris[J].mBio,2020,11(3):e00365-00320.

[24] KANNAN A,ASNER S A,TRACHSEL E,et al.Comparative genomics for the elucidation of multidrug resistance in Candida lusitaniae[J].mBio,2019,10(6):e02512-02519.

[25] HOU X,HEALEY K R,SHOR E,et al.Novel FKS1 and FKS2 modifications in a high-level echinocandin resistant clinical isolate of Candida glabrata[J].Emerg Microbes Infec,2019,8(1):1619-1625.

[26] LEE K K,KUBO K,ABDELAZIZ J A,et al.Yeast species-specific,differential inhibition of β-1,3-glucan synthesis by poacic acid and caspofungin[J].The Cell Surface,2018,3:12-25.

[27] KAPOOR M,MOLONEY M,SOLTOW Q A,et al.Evaluation of resistance development to the Gwt1 inhibitor manogepix (APX001A) in Candida species[J].Antimicrob Agents Chemother,2019,64(1):e01387-01319.

[28] HUANG C Y,CHEN Y C,WU HSIEH B A,et al.The ca-loop in thymidylate kinase is critical for growth and contributes to pyrimidine drug sensitivity of Candida albicans[J].J Biol Chem,2019,294(27):10686-10697.

[29] SUN Q Q,XIONG K,YUAN Y C,et al.Inhibiting fungal echinocandin resistance by small-molecule disruption of geranylgeranyltransferase type I activity[J].Antimicrob Agents Chemother,2020,64(2):e02046-02019.

[30] DEMUYSER L,PALMANS I,VANDECRUYS P,et al.Molecular elucidation of riboflavin production and regulation in Candida albicans,toward a novel antifungal drug target[J].mSphere,2020,5(4):e00714-00720.

[31] KLEINSTIVER B P,PREW M S,TSAI S Q,et al.Engineered CRISPR-Cas9 nucleases with altered PAM specificities[J].Nature,2015,523(7561):481-485.

[32] HU J H,MILLER S M,GEURTS M H,et al.Evolved Cas9 variants with broad PAM compatibility and high DNA specificity[J].Nature,2018,556(7699):57-63.

[33] DEVEAU H,BARRANGOU R,GARNEAU J E,et al.Phage response to CRISPR-encoded resistance in Streptococcus thermophilus[J].J Bacteriol,2008,190(4):1390-1400.

[34] CHO S W,KIM S,KIM Y,et al.Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases[J].Genome Res,2014,24(1):132-141.

[35] FU Y F,SANDER J D,REYON D,et al.Improving CRISPR-Cas nuclease specificity using truncated guide RNAs[J].Nat Biotechnol,2014,32(3):279-284.

[36] IANIRI G,DAGOTTO G,SUN S,et al.Advancing functional genetics through agrobacterium-mediated insertional mutagenesis and CRISPR/Cas9 in the commensal and pathogenic Yeast Malassezia[J].Genetics,2019,212(4):1163-1179.

[37] WANG Q,COLEMAN J J.CRISPR/Cas9-mediated endogenous gene tagging in Fusarium oxysporum[J].Fungal Genet Biol,2019,126:17-24.DOI:10.1016/j.fgb.2019.02.002.

[38] KUJOTH G C,SULLIVAN T D,MERKHOFER R,et al.CRISPR/Cas9-mediated gene disruption reveals the importance of zinc metabolism for fitness of the dimorphic fungal pathogen Blastomyces dermatitidis[J].mBio,2018,9(2):e00412-00418.